Abstract
Calcium triflate has been identified as an efficient catalyst for the cycloaddition of nitrones to donor–acceptor cyclopropanes. The reaction proceeds with good to excellent yields of the corresponding tetrahydro-1,2-oxazines with high levels of diastereoselectivity. The generality of the reaction allowed for the synthesis of tetrahydro-1,2-oxazines bearing alkyl, aryl, and heteroaromatic substitution.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have