Abstract
New enzymes screened for specific conversions have been purified and characterized from various microorganisms, and successfully applied to organic synthesis. These include : 1) nitrile hydratase from Arthrobacter sp. and Pseudomonas chlororaphis, useful in the hydration of nitriles to produce amides, 2) NAD+-dependent phenylalanine dehydrogenase from Sporosarcina ureae and Bacillus sphaericus, useful in the reductive amination of phenylpyruvate to give L-phenylalanine, 3) D-aminpeptidase from Achromobacter sp. applicable to the kinetic resolution of amino acid amides to give D-amino acid, and the D-stereospecific aminolysis reaction in organic solvents of amino acid esters or amides to yield D-amino acid N-alkylamides.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
