Abstract
3-Methyl-1-(4-pyridinyl)-2-butanone has been synthesized via a short and convenient method based upon acylation of 4-picoline by phenyllithium followed by reaction with ethyl isobutyrate. This procedure can be extended to the preparation of various alkyl pyridyl ketones, intermediates in the synthesis of potential anti-tumor 6-substituted 7H-pyridocarbazole dimers.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have