Abstract
Abstract The aldol reactions of boron enolates derived from a hydantoin chiral auxiliary derived from l -phenylalanine occur in good yields with high syn diastereoselectivity. Aldol adduct 4a is readily cleaved by hydrolysis to afford (2 S ,3 S )-3-hydroxy-2-methyl-3-phenylpropionic acid 5a in good yield and in almost enantiomerically pure form.
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