Abstract
Abstract Asymmetric trans-addition reactions of (E)-phenylpropene, a mechanistically novel reactions, have been achieved by using chiral selenium-containing binaphthyl derivatives. Introduction of an amide group at 2′-position in the binaphthyl skeleton enhances considerably the diastereomeric excess (d.e.) of the asymmetric reaction presumably due to attractive interaction between the nitrogen lone pair and the seleniranium intermediate. Introduction of another chiral center in the amide group further enhances the d.e. as high as 79 %, which is the highest asymmetric induction ever achieved in the asymmetric trans-addition reaction.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
