ChemInform Abstract: Asymmetric Synthesis via Heterocyclic Intermediates. Part 39. Asymmetric Synthesis of (Enantiomerically and Diastereomerically Virtually Pure) Methyl 2‐Amino‐4,5‐epoxy‐3‐hydroxy‐alkanoates and Methyl 2‐Amino‐3‐hydroxy‐4,5‐methylene‐alkanoates by the Bislactim Ether Method.

Abstract

AbstractThe titanated bislactim ether (I) of cyclo‐(L‐Val‐Gly) reacts with various unsaturated aldehydes (III) to give the adducts (IV).