Abstract
A novel L-proline-catalyzed mild and ecological approach towards the synthesis of 2H-chromene derivatives was achieved by Knoevenagel reaction followed by an intramolecular hemiketalization process. In the present protocol, chemoselectivity has been successfully achieved by using L-proline as catalyst. This eco-friendly and chemoselective reaction provided an alternative synthetic method to prepare previously unknown 2H-chromene derivatives in a one-pot reaction.
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