ChemInform Abstract: AN ALTERNATIVE ROUTE TO YOMOGI ALCOHOL

Abstract

Abstract On the basis of spectral data plus results of selective partial hydrogenation, yomogi alcohol, a new artemisia-type monoterpene originally considered to have structure I,1 was reformulated as II.2 Meanwhile, Willhalm and Thomas3 and later Thomas and Pawlak4 reported a nonselective synthesis of II along with a study of its chemistry. Independently, Sucrow5 developed a specific route to II and also a synthesis of I. Here we report an efficient, alternative two-step synthesis of II starting from 3,3-dimethylpent-1-en-4-yne (III).6