Abstract
Alstoscholarisine F (1), a monoterpenoid indole alkaloid pigment with unprecedented carbon skeleton, and alstoscholarisine G (2) incorporated with a third nitrogen atom were isolated from the long-term stored leaves of Alstonia scholaris. Their structures were established by extensive MS and NMR spectroscopic analysis and the absolute configuration of 1 was defined by comparison of experimental and calculated ECDs. Compounds 1 and 2 were subjected to hippocampal neuronal stem cells (NSCs) proliferation evaluation, but they did not show significant effect. (C) 2015 Elsevier Ltd. All rights reserved.
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