Abstract
We present a one-pot method for the synthesis of 2,3-dihydroquinazoline-4(1H)-ones. The three-component reaction between isatoic anhydride, primary amines, and dialkyl acetylenedicarboxylates in the presence of N-sulfonic acid pyridinium chloride under solvent-free conditions affords the corresponding alkyl 2-[(alkoxycarbonyl)methyl]-1,2,3,4-tetrahydro-3-alkyl-4-oxo-quinazoline-2-carboxylates in excellent yields.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
