Abstract
The formation of reactive O 2 species in the pancreas of pigs after induction of necrotizing or oedematous pancreatitis was studied by means of luminol- and lucigenim-sensitized chemiluminescence. The effect of 2,2-dimethyl-4-methanesulphonic acid-1,2-dihydroquinoline in combination with Trasylol and ascorbic acid was studied in vivo. This combined therapy leads to a reaction in the chemiluminescence response by 50–70% with prevention of pancreatogenic shock and multiple organ failure by improvement of the glutathione status. The combination of radical traps, kallikrein inhibitors and natural antioxidative substances is an efficient alternative therapy in cases of acute pancreatitis.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
