Abstract

ABSTRACT To the Editor: —In The Journal (152:353 [May 23] 1953), there was a note concerning the report of a case in the Lancet (1:577, 1953) in which eczema, mental depression, and anorexia associated with the ingestion of chemically treated developed. The authors concluded, after presenting their findings, that the patient showed an allergic response to wheat flour treated with nitrogen trichloride or chlorine dioxide. In addition, they asked whether this is a rare case of allergy or merely the first recognition of a common disorder. In 1949, I published a paper on the Species Specificity of Agene Toxicity in the Journal of Applied Physiology (p. 802) and reported that the ingestion over a period of time of over one half of the initial body weight of bread and cookies made with wheat flour that had been very heavily treated with nitrogen trichloride (Agene) had no ill effect on

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