Abstract

One juvenile hormone was isolated from culture medium containing isolated corpora allata of the grasshopper Schistocerca vaga (Orthoptera: Acrididae) and was shown by microchemical methods to be methyl (2 E , 6 E ) - (10 R ) - 10, 11-epoxy-3, 7, 11-trimethyldodeca-2, 6-dienoate. This compound (JH III), which occurs in a sphingid moth Manduca sexta , is the first juvenile hormone identified in an insect order other than the Lepidoptera. Grasshopper organs incorporate both [2− 14C] acetate and [methyl- 14C] methionine into JH III showing de novo biosynthesis, but no indication of the synthesis of JH I or JH II was seen.

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