Abstract

The chemical states of iron contained in tissues obtained from a patient with parkinsonism-dementia complex (PDC) were investigated using micro beams from a synchrotron radiation source. XRF analyses were performed at energies 7.160 keV, highly above the iron absorption edge, and 7.120 keV, slightly above the Fe2+ absorption edge to suppress the excitation of Fe3+. Iron was detected in neuromelanin granules and one of glial cells in the PDC tissue. The results show differences in the chemical state of the iron in the neuromelanin granules and the glial cells. The Fe3+/Fe2+ ratio of iron contained in the glial cell is considerably higher than that of the neuromelanin granules.

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