Abstract

ObjectiveThis review was prepared to offer the most complete information about the use of ondansetron in parenteral admixtures with other drugs. MethodThe search was done from September 2016 to April 2017 by using electronic databases Stabilis® and Micromedex® solutions, Medli- ne/PubMed and Scholar Google searching publications about ondansetron stability in parenteral infusion when is administered by itself or with other medication. Results49 studies are included with a total of 53 drugs. 15 drugs were found compatible administered with ondansetron in a clinical routine concentration range in intravenous administration. Also, four ternary blends were found compatible and another one was incompatible. Otherwise, 38 drugs were found incompatible. ConclusionsCompatibility of ondansetron offers a broad number of options to be used to avoid nausea and vomiting symptoms in patients with other concomitant medication.

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