Abstract
Chemical stability is a key component of ensuring that a cosmetic product is safe for consumer use. The objective of this study was to evaluate the chemical stability of commercially available hair cleansing conditioners subjected to high heat stresses from the styling processes of blow drying or straightening. Two hair cleansing conditioners were subjected to temperatures of 60 °C and 185 °C to simulate the use of a blow dryer or flatiron hair straightener, respectively and analyzed via Gas Chromatography-Mass Spectrometry (GC-MS), High-Performance Liquid Chromatography-UV (HPLC) and Fourier-Transform Infrared Spectroscopy (FT-IR) to capture a chemical profile of the samples. The resulting spectra from matched heated and unheated samples were compared to identify any changes in chemical composition. Overall, no differences in the spectra were observed between the heated and unheated samples at both temperatures evaluated. Specifically, no new peaks were observed during analysis, indicating that no degradation products were formed. In addition, all chemicals identified during GC-MS analysis were known listed ingredients of the products. In summary, no measurable changes in chemical composition were observed in the hair cleansing conditioner samples under high-heat stress conditions. The presented analytical methods can serve as an initial screening tool to evaluate the chemical stability of a cosmetic product under conditions of anticipated use.
Highlights
Personal care and cosmetic products are widely used throughout the world, with an estimated worldwide revenue of $265 billion in 2017 [1]
Current regulatory standards, such as those issued by the Food and Drug Administration (FDA) in the United States or the European Union, do not require specific testing to demonstrate the safety of personal care and cosmetic products or ingredients [2,3]
This study demonstrates the use of analytical methods to examine the chemical stability of a personal product under simulated use
Summary
Personal care and cosmetic products are widely used throughout the world, with an estimated worldwide revenue of $265 billion in 2017 [1] Current regulatory standards, such as those issued by the Food and Drug Administration (FDA) in the United States or the European Union, do not require specific testing to demonstrate the safety of personal care and cosmetic products or ingredients [2,3]. Trade industry associations—such as the Personal Care Products Council (PCPC) in the United States and Cosmetics Europe in Europe—have developed resources for industry members to ensure the safety of personal care and cosmetic products These guidelines include product stability testing, with the goal of ensuring that a “cosmetic product maintains its intended physical, chemical and microbial quality, as well as functionality and aesthetics when stored under appropriate conditions” [4].
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