Abstract
The chemical shift order of axial and equatorial methylene protons in 1,5-disubstituted 3,7-diazabicyclo[3.3.1]nonan-9-ones may be altered by substituents in the 1,5-positions, but the corresponding alcohols behave differently. Unambiguous signal assignments for a series of the title compounds are provided, based on 3JCH coupling constants and on {1H} 13C heteronuclear Overhauser effects. Substituent anisotropy effects as a source of the chemical shift changes are discussed. © 1997 by John Wiley & Sons, Ltd.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
