Abstract

A polysaccharide with an estimated weight-average molar mass of 4.6×10 5 was obtained from an aqueous extract of pseudobulbs of Cyrtopodium cardiochilum Lindl. by fractionation on Sephacryl S-300 HR and Sephadex G-25. Chemical and spectroscopic studies indicated that it has a backbone of (1→4)-linked β- d-mannopyranosyl residues and β- d-glucopyranosyl residues, and is demonstrated to be composed of d-mannose and d-glucose in 2:1 molar ratios. It was found to contain 4.2% of acetyl groups substituted at O-2 of (1→4)-linked β- d-Man p and β- d-Glc p. The polysaccharide inhibits capillary permeability and demonstrates phagocytosis stimulating property.

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