Abstract
The effect of various metal compounds, formaldehyde and adriamycin on the rejoining of X-rays induced DNA single strand breaks was examined using the alkaline elution technique. of the compounds tested, Chromate, mercury (II) and formaldehyde decreased the ability of cells to rejoin DNA strand breaks. The inhibition of DNA repair could be demonstrated also using another system where strand breaks were produced by exposing cells for 1 hr. to 30 HM H2O2, at ice temperature.
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