Abstract

This article describes our work on the BioCreative-V chemical–disease relation (CDR) extraction task, which employed a maximum entropy (ME) model and a convolutional neural network model for relation extraction at inter- and intra-sentence level, respectively. In our work, relation extraction between entity concepts in documents was simplified to relation extraction between entity mentions. We first constructed pairs of chemical and disease mentions as relation instances for training and testing stages, then we trained and applied the ME model and the convolutional neural network model for inter- and intra-sentence level, respectively. Finally, we merged the classification results from mention level to document level to acquire the final relations between chemical and disease concepts. The evaluation on the BioCreative-V CDR corpus shows the effectiveness of our proposed approach. Database URL: http://www.biocreative.org/resources/corpora/biocreative-v-cdr-corpus/

Highlights

  • Understanding chemical–disease relations (CDRs) is crucial in various areas of biomedical research and health care [1,2,3]

  • We mainly focus on the chemical-induced disease (CID) relation extraction task

  • We present our approach for the CID relation extraction subtask of the BioCreative-V CDR task

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Summary

Introduction

Understanding chemical–disease relations (CDRs) is crucial in various areas of biomedical research and health care [1,2,3]. Due to the high cost of the manual curation, several attempts have been made on automatic biomedical information extraction with some promising results using text-mining technologies [6,7,8,9]. Many tasks such as identifying biomedical concepts [10, 11] and extracting relations between biomedical entities [12], still remain challenging. The task consisted of two subtasks: the disease named entity recognition task and the chemical-induced disease (CID) relation extraction

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