Abstract
Introduction: Dendriscosticta is a new genus belong the Sticta wrightii group of the family Lobariaceae. This genus of foliose lichen is widely distributed in tropical regions worldwide. The lichen Dendriscosticta platyphylloides is very abundant in Bidoup forest, Lam Dong province, Vietnam.
 Methods: The structure of these compounds was elucidated through the interpretation of their 1D and 2D-NMR and HR-MS data. The cytotoxic activities of these compounds against liver hepatocellular carcinoma (HepG2), human lung cancer (NCI-H460), human epithelial carcinoma (HeLa) and human breast cancer (MCF-7) cell lines was performed at the concentration of 100 mg/mL using the sulforhodamine B (SRB) assay.
 Results: In this paper, we reported the isolation of six known compounds, including (1) 15a-acetoxyhopan-22-ol (2) hopane-15a,22-diol, (3) zeorin, (4) cerevisterol, (5) salvigenin, and (6) 5-hydroxy-3',4',7-trimethoxyflavone.
 Conclusion: This is the first time that these compounds are isolated from Dendriscosticta genus. These compounds showed no cytotoxic activity against four cell lines.
Highlights
Dendriscosticta is a new genus belong the Sticta wrightii group of the family Lobariaceae
The cytotoxic activities of these compounds against liver hepatocellular carcinoma (HepG2), human lung cancer (NCI-H460), human epithelial carcinoma (HeLa) and human breast cancer (MCF-7) cell lines was performed at the concentration of 100 μg/mL using the sulforhodamine B (SRB) assay
In this paper, we reported the isolation of six known compounds, including (1) 15α-acetoxyhopan-22-ol (2) hopane-15α,22-diol, (3) zeorin, (4) cerevisterol, (5) salvigenin, and (6) 5-hydroxy-3',4',7-trimethoxyflavone
Summary
Dendriscosticta is a new genus belong the Sticta wrightii group of the family Lobariaceae. This genus of foliose lichen is widely distributed in tropical regions worldwide. Conclusion: This is the first time that these compounds are isolated from Dendriscosticta genus. These compounds showed no cytotoxic activity against four cell lines. In the course of our systematic research on lichen substances from the Vietnamese flora, we have examined Dendriscosticta platyphylloides which is widely distributed in the southwestern part of the central of Vietnam and has not yet been chemically and biologically studied. According to Rober Lucking 4, Dendriscosticta is a new genus belong the Sticta wrightii group within Lobaria clade. The primary goal of the present work was to study chemical constituent of the lichen Dendriscosticta platyphylloides (Nyl.) Moncada & Lücking
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