Abstract
Phytochemical investigation of the dried roots of Euphorbia kansui resulted in the isolation of three flavonoids (1-3), three diterpenoids (4-6) and five triterprnoids (7-11). Among them, three compounds (1-3) were firstly isolated from the family Euphorbiaceae. Others were reported in the genus Euphorbia, in which three compounds (8-11) were firstly isolated from the E. kansui. The chemotaxonomic significance of these compounds was summarized.
Highlights
The plants of Euphorbia contain more than 2000 species spread all over the world, and about80 species distribute in China [1,2]
HPLC: Hanbon NP 7000 (Jiangsu Hanbang Technology Companies, Huaian, China) Serials pump with an NU 3000 Serials UV-Vis detector (Jiangsu Hanbang Technology Companies, Huaian, China), Phecda Si (20 × 250 mm, 5 μm); Waters 1525 with a 2996 Diode Array Detector (DAD) (Waters, Milford, CT, USA), XBrige-Prep C18 (150 × 19 mm, 5 μm), (Ultimate XB-C8, 30 × 150 mm, 5 μm)
The dried root of Euphorbia kansui was collected from Red River valley of Baoji, Shaanxi
Summary
The plants of Euphorbia contain more than 2000 species spread all over the world, and about. 80 species distribute in China [1,2]. The structure type of the compounds in Euphorbia kansui are diterpenes, triterpenes, flavonoids, phenolic and acids [3,4,5]. Diterpenes and triterpenoids are the main compounds in Euphorbia kansui, which show a wide range of pharmacological activities, such as antiviral, skin irritating and modulation of multidrug resistance effects [6,7,8,9]. A new tirucallane-type triterpene named tirucalla-8,24-diene-3β,11β-diol-7-one (1) was first isolated from natural plants, and an euphane-type triterpene named eupha-8,24-diene-3β,11β-diol-7-one (2) (Figure 1) was isolated from Euphorbia kansui for the first time in our present study.
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