Chemical constituents from the aerial parts of Salsola inermis

Abstract

Background and objective The hydroalcoholic extract from the aerial parts of Salsola inermis exhibited antioxidant, anti-inflammatory, and antinociceptive effects. The present study deals with the isolation and identification of the chemical constituents of this hydroalcoholic extract. Materials and methods The aerial parts of S. inermis (Forsskal) were collected from wild plants growing near the El-Alamein area in October 2005. Air-dried and powdered aerial parts of S . inermis were extracted with 70% alcohol in H 2 O. The extract was partitioned successively with CHCl 3 , EtOAc, and n -BuOH. The structures of the isolated compounds were determined by chemical and spectroscopic analyses. Results and conclusion Phytochemical investigation of the alcoholic extract from the aerial parts of S. inermis revealed 12 compounds, identified as long chain hydroxyl fatty acid 9,12,13-trihydroxydecosan–10,15,19-trienoic acid; trans - N -feruloyl tyramine-4ooo- O -β-D-glucopyranoside; umbelliferone; scopoletin; 3-methyl kaempferol; olean-12-en-3,28-diol; olean-12-en-28-oic acid; stigmasterol-3-β- O -D-glucopyranoside; 3- O -[β-D-glucopyranosyl]oleanolic acid; kaempferol 3-O-β-glucopyranoside; and isorhamnetin 3- O -β-glucopyranoside, in addition to β-sitosterol, stigmasterol, and stigmastanol. Some of these compounds have hydroxyl groups, which help in scavenging free radicals and inhibit COX and various mediators involved in the pathogenesis of pain relief.