Chemical constituents from the aerial parts of Launaea sarmentosa (Asteraceae)

Abstract

The phytochemical investigation of the aerial parts of Launaea sarmentosa (LS) led to the isolation of two new compounds (2 and 11) along with 14 known compounds (1, 3–10, and 12–16). The structures of these compounds were determined through 1D and 2D-NMR spectroscopic analysis, MS, electron circular dichroism spectra calculations, and comparison with published spectroscopic data. The isolated compounds include methyl pyroglutamate (1), sarmentosin A (2), caffeic acid (3), ferulic acid (4), umbelliferon (5), esculetin (6), α-conidendrin (7), apigenin (8), luteolin (9), quercetin (10), sarmentosin B (11), cynaroside (12), luteolin 7-O-rutinoside (13), rutin (14), lupeol (15), and β-sitosterol (16). Compounds 1 and 7 were isolated from the Launaea genus for the first time, while compounds 3–6, 8, 10, and 12–16 were reported for the first time in this species.