Abstract

The phytochemical investigation on Mesua lepidota T. Anderson led to the identification of eight Mammea coumarins [lepidotols A-B (1–2), lepidotol E (3), lepidotins A-C (4–6), mammea A/BB cyclo F (7), and ochrocarpin E (8)], five triterpenes [friedelin (9), friedelinol (10), betulinic acid (11), glutinol (12), and α-amyrin (13)], one xanthone, namely pyranojacareubin (14), and two sterols [β-sitosterol (15) and stigmasterol (16)]. Identification was conducted by 13C-NMR dereplication and after a conventional isolation process. The structural elucidation of the isolated compounds was conducted through the analysis of spectroscopic data and comparison with literature data. The chemotaxonomic significance of all compounds was discussed, highlighting that most compounds were isolated only in the Mesua genus, or specifically from Mesua lepidota. In addition, glutinol (12) was isolated for the first time from the genus Mesua.

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