Chemical constituents from a Chinese fern Polypodium hastatum Thunb.

Abstract

Phytochemical investigation on a Chinese fern Polypodium hastatum resulted in the isolation of three flavonoid glycosides, one steroid and one coumarin. Their structures were identified as β-sitosterol ( 1 ), coumarin ( 2 ), juglanin ( 3 ), kaempferol-7-O-α- l -rhamnopyranoside ( 4 ) and (+)-afzelechin-5-O-β- d -apiofuranoside ( 5 ) on the basis of spectroscopic analysis including UV, MS, 1D and 2D NMR, and chemical and physical properties. (+)-Afzelechin-5-O-β- d -apiofuranoside was a new flavonoid glycoside. Chemotaxonomic significance of this investigation was summarized. ► Chemical constituents from Polypodium hastatum Thunb. were investigated. ► Five compounds including a new flavonoid glycoside were identified. ► Chemotaxonomic significance of relevant chemical constituents was summarized.