Abstract
Two butanolides, subamolide D 1 and subamolide E 2, along with β-sitosterol 3, β-sitostenone 4, lupeol 5, taraxerol 6, and 24-methylenelanosta-7,9(11)-diene-3β,15α-diol 7 were isolated from the leaves of B eilschmiedia glabra . The structures of the isolated compounds were elucidated by extensive spectroscopic data analysis and comparison with respective literature data. The compounds were tested for DPPH radical scavenging, antimicrobial, acetylcholinesterase and lipoxygenase inhibitory activities. Compounds 1-2 displayed the strongest lipoxygenase assay with an IC 50 value of 5.1 and 5.5 μM, respectively. All compounds showed weak activity on DPPH radical-scavenging, antimicrobial, and acetylcholinesterase inhibition assay.
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