Abstract
Introduction: Present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oil from Mentha longifolia (L.) Huds. Aim of this study to investigate the quality, antimicrobial andantioxidant activity of wild species Mentha longifolia essential oil from Bosnia and Herzegovina.Methods: The chemical profi le of essential oil was evaluated by the means of gas chromatography-mass spectrometry (GC-MS) and thin-layer chromatography (TLC). Antimicrobial activity was tested against 6bacterial strains. RSC was assessed by measuring the scavenging activity of essential oils on 2,2- diphenyl-1-picrylhydrazil (DPPH).Results: The main constituents of the essential oil of M. longifoliae folium were oxygenated monoterpenes,piperitone oxide (63.58%) and 1,8-cineole (12.03%). Essential oil exhibited very strong antibacterial activity.The most important antibacterial activity essential oil was expressed on Gram negative strains: Escherichia coli, Pseudomonas aerginosa and Salmonella enterica. subsp.enterica serotype ABONY. Antioxidant activity was evaluated as a RSC. Investigated essential oil was able to reduce DPPH radicals into the neutral DPPHH form (IC50=10.5 μg/ml) and this activity was dose –dependent.Conclusion: The study revealed signifi cant antimicrobial activity of the investigated essential oil. The examined oil exhibited high RSC, which was found to be in correlation to the content of mainly monoterpeneketones and aldehydes. These results indicate that essential oils could serve as safe antioxidant and antiseptic supplements in pharmaceuticals.
Highlights
Present study describes the antimicrobial activity and free radical scavenging capacity (RSC)of essential oil from Mentha longifolia (L.) Huds
The most important antibacterial activity essential oil was expressed on Gram negative strains: Escherichia coli, Pseudomonas aerginosa and Salmonella enterica. subsp.enterica serotype ABONY
These results indicate that essential oils could serve as safe antioxidant and antiseptic supplements in pharmaceuticals
Summary
Present study describes the antimicrobial activity and free radical scavenging capacity (RSC)of essential oil from Mentha longifolia (L.) Huds. Aim of this study to investigate the quality, antimicrobial and antioxidant activity of wild species Mentha longifolia essential oil from Bosnia and Herzegovina. Submitted 21 September 2012 / Accepted 30 November 2012 demonstrated biological activities. Among these various kinds of natural substances, essential oils from aromatic and medicinal plants receive particular attention as potential natural agents for food preservation. Their effectiveness against a wide range of microorganisms has been repeatedly demonstrated [2,3,4,5]. Biologically active natural compounds are of interest to the pharmaceutical industry for the control of human diseases of microbial origin and for the prevention of lipid peroxidative dam-
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have