Abstract
Abstract—The review integrates information on the studies of component composition and biological activity of some Astragalus L. (Fabaceae) species published over the last 5–7 years. The aerial and underground parts of 34 Astragalus species contain triterpene saponins, flavonoids, polisaccharides, tannins, free organic acids, higher fatty acids, vitamins, trace elements, and other constituents. Among Astragalus species, the best studied in relation to component composition and biological activity is A. membranaceus (Fisch.) Bunge. In vitro and in vivo experimental studies suggest that total amount of bioactive substances, fractions of and individual compounds extracted from different parsts of A. membranaceus and A. membranaceus var. mongholicus exhibit anti-inflammatory, immunomodulatory, antioxidant, anticancer, cardiportactive, and hepathoprotective activity. The composition and biological effects of other Astragalus species have been little studied. The review synthesizes recent advances in the studies of new compounds extracted from Astragalus species, and on their biological activity.
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