Chemical composition and larvicidal activity against Aedes aegypti larvae from Hyptis suaveolens (L.) Poit essential oil

Abstract

Mosquito borne diseases remain a global public health issue and effective vaccines and treatments are often unavailable. Biopesticides isolated from plants have been effectively used to protect humans from mosquito bites through insecticide-treated mosquito nets, fabrics, and indoor sprays. It is known that extensive usage of chemical insecticides has caused serious health problems to humans and animals. In this perspective, demand for essential oils has risen in recent years throughout the globe. The intent of the contemporary research was to determine the potency of an Hyptis suaveolens (L.) Poit., essential oil against the Aedes aegypti which belongs to the family Lamiaceae (syn. Labiatae), which is known for its abundance of medicinal species. The essential oil from H.suavelolens was isolated using a simple, environmentally friendly protocol. In total, 11 compounds were identified by using GC-MS. The FTIR spectra validated and assisted the GC-MS data by showing functional group stretching with aromatic groups. The larvicidal operation of 12 h and 24 hr exposure cycles of 3rd instar larvae exhibit the maximum fatality rate at 100 PPM (LC50 of 32.85 PPM) and (LC90 of 66.54 PPM). Essential oil has a higher degree of activity in terms of cell damage, according to histological studies, and oil deposition was seen in the midgut and cortex. The current method will create an environmentally sustainable synthesis of H. suavelolens essential oil and their efficacy of antioxidant and larvicidal function.