Abstract
The South African medicinal plant Oncosiphon suffruticosum (L.) Källersjö is an important remedy used to treat chronic, respiratory, and skin ailments. From the essential oil (EO) extracted by the hydrodistillation, sixteen constituent components were identified with oxygenated monoterpenes: camphor (31.21%), filifolone (13.98%), chrysanthenone (8.72%), 1,8-cineole (7.85%), and terpinen-4-ol (7.39%) as predominant constituents. In the antibacterial activity study, the EO was found most susceptible against Pseudomonas aeruginosa with an MIC of 6.4 mg/mL; however, it showed the same activity against Staphylococcus aureus and Escherichia coli with an MIC value of 12.8 mg/mL. The sun protecting factor (SPF) of the EO was found to be 2.299 and thus establishing it as a potentially important cosmeceutical for sunscreen applications. This is the first report investigating the essential oil of O. suffruticosum for its chemical composition and skin-related in vitro biological activities viz antibacterial, antioxidant capacity, antityrosinase, and sun protection factor.
Highlights
Essential oils (EOs) are aromatic oily liquids composed of a complex mixture of volatile compounds and are produced by aromatic plants as secondary metabolites
The small lipophilic molecules that make up their composition grant easy penetration through the skin layers [14]
The present work is the first report to investigate the chemical composition of O. suffruticosum essential oil and its biological activities to explore its cosmeceutical potential in selected biological activities of dermatological relevance
Summary
Essential oils (EOs) are aromatic oily liquids composed of a complex mixture of volatile compounds and are produced by aromatic plants as secondary metabolites. The volatile constituents of EOs have been important materials for preventing and treating human diseases since the early days [1]. Research backs up their efficacy as valuable cosmeceuticals. They have been shown to exhibit properties of antimicrobials [2,3], antioxidant agents [4,5], antityrosinase agents [6,7,8], sunscreens [9,10], natural preservatives [11], natural sources of fragrance [12], as well as inhibitors of skin’s degradation enzymes (collagenase and elastase) [13]. The small lipophilic molecules that make up their composition grant easy penetration through the skin layers [14]
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