Abstract

Plants of the genus Campomanesia (Myrtaceae) are traditionally used for medicinal purposes, with biological activities associated with the presence of phenolic compounds. However, the species Campomanesia guazumifolia (Cambess.) O. Berg still needs studies regarding both chemical composition and biological activities. In this context, the study aimed to analyze the chemical composition by UV/Vis, infrared and UHPLC-DAD and the antioxidant and antimicrobial potentials of the infusion of leaves of C. guazumifolia. The DPPH•, ABTS•+, and FRAP methods determined the antioxidant potential. The lethal dose (LD50) in Artemia salina L. (Artemiidae) and minimum inhibitory concentration (MIC) in bacteria and fungus were determined. Gallic acid, caffeine, and rutin were quantified, as well as 9 amino acids. This is the first report of caffeine within the genus Campomanesia. The sample showed antioxidant potentials, low toxicity to A. salina, and antimicrobial activity against bacterias Bacillus cereus and Staphylococcus aureus and fungus Candida albicans, C. krusei, C. parapsilosis, and C. tropicalis. The infusion of C. guazumifolia leaves is a nutraceutical tea with antioxidant and antimicrobial potentials and presents phenolic compounds, amino acids and caffeine in its composition.

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