Abstract
This study examined the phytochemicals and medicinal potentials of the leaf essential oil of E. maculata from Nigeria. The essential oil was extracted by hydro-distillation technique and was analysed for various chemical composition using GC-MS. The essential oil was also screened for its antimicrobial activities against multi-drug resistant gram-positive and gram-negative bacteria using the agar well diffusion method. The GC-MS analysis revealed that s-citronellol (18.5%), s-pinene (9.4%), 2,6-dimethyl-2,6-octadiene (8.3%), a-pinene (7.1%), 2,6-dimethyl-1,3,5,7- octatetraene (6.7%), and citronellyl acetate (6.0%) were the major compounds in the leaf essential oil. The essential oil exhibited strong antibacterial activities against most of the tested bacteria, with diameters of inhibition zones ranging from 15.0-30.0 mm. The leaf essential oil of E. maculata is a possible alternative antibiotic drug for treatment of disease caused by multi-drug resistant bacteria.
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