Abstract

The chemical constituents of essential oils obtained from Ficus asperifolia and Ficus capensis by hydrodistillation were determined by using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) techniques. Antimicrobial activity was evaluated by means of disc diffusion method against seven clinically important bacterial and two fungi strains. The main constituents of F. asperifolia were myristicin (16.4%), limonene (15.7%), phytol (11.1%), methyl salicylate (10.8%) and cyclododecane (9.9%). However, tricosane (52.2%), hexacosane (24.2%) and cyclcotetradecane (15.4%) were the principal constituents of F. capensis. The results also showed that both oils exhibited wide range of antimicrobial activity against the tested organisms. The zones of inhibition (IZ) ranged between 8.7 ± 3.1 and 28.3 ± 0.6 mm in F. capensis; and 9.3 ± 0.2 and 26.3 ± 5.5 mm in F. asperifolia, while, the minimum inhibitory concentrations (MIC) values varied between 0.08 and 10.0 mg/mL (F. capensis) and 0.16 and 10 mg/mL (F. asperifolia).

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