Abstract

Meeting abstracts Many mouse models of breast cancer have been developed that closely replicate human breast cancer subtypes at the genomic level. In order to develop vaccines that could prevent a broad spectrum of breast cancer subtypes, a combination of different spontaneous tumor models are

Highlights

  • Many mouse models of breast cancer have been developed that closely replicate human breast cancer subtypes at the genomic level

  • In order to develop vaccines that could prevent a broad spectrum of breast cancer subtypes, a combination of different spontaneous tumor models are needed

  • In order to address the utility of the DMBA model for vaccine studies, we performed experiments to look at the effect of DMBA on the immunogenicity of breast cancer vaccines

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Summary

Introduction

Many mouse models of breast cancer have been developed that closely replicate human breast cancer subtypes at the genomic level. Chemical carcinogens used to induce spontaneous tumors may suppress tumor specific T-cell immunity From Society for Immunotherapy of Cancer 28th Annual Meeting National Harbor, MD, USA.

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