Abstract
BACKGROUND:Among the therapeutic possibilities for onychomycosis, chemical nail avulsion is a logical approach to the eradication ofthe pathogen.METHODS: A new formulation was used as a nail lacquer containing 40% urea in a film-forming solution in 10 patients presenting with onychomycosis. The urea nail lacquer was applied with a brush twice a day for 1 week by the patient and for a further week in two patients presenting total dystrophic onychomycosis.RESULTS: This transungual delivery system weakens the nail plate/nail bed attachment in the diseased area.CONCLUSION: The urea nail lacquer is comfortable for the patient and allwos easy removal of the fungal nail plate.
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