Abstract

Five metabolites, a diglyceride ester (1), cholesterol (2), 24-methylene cholesterol (3) Δ5-3β-Hydroxy-7-ketosterol (4) and asebotin (5) were isolated for the first time from the Red Sea grass Thallasodendron ciliatum and characterized. GLC analysis of the unsaponifiable matter revealed that it contained a high percentage of hydrocarbons (59.47%) with n-hexacosane as a major component (10.98%). Furthermore, cholesterol (23.37%) was the major identified sterol. GLC analysis of the fatty acid methyl esters revealed that arachedic acid is the major fatty acid (63.78%). Crude extract showed antifungal activity against Candida krusei and C. krusei with percent growth inhibition of 85 and 77, respectively. Compounds 1 and 5 showed good anti-oxidant properties.

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