Abstract

Extract of Agaricus silvaticus Schaeff ex. Secr fungus have been known to have biological activities, including antibacterial, antiviral, anticancer, antioxidant, anticomplementary and immunostimulating effects. In this study we first time identified that Agaricus silvaticus Schaeff ex. Secr has interferon like activity. We first time isolated the four known compounds such as, mannitol (1), urea (2), ergosterol (3) and ergosterol peroxide (4) from 95% ethanol extracts of Agaricus silvaticus Schaeff ex. Secr in Mongolia. Their structures were elucidated on the basis of extensive analysis of spectral data and by comparison with authentic samples.DOI: http://dx.doi.org/10.5564/mjc.v12i0.180 Mongolian Journal of Chemistry Vol.12 2011: 92-97

Highlights

  • Mushrooms are considered nutraceuticals or functional foods by many clinicians and researchers, a fact that has stimulated the search by Brazilian producers for more advanced production techniques along with introduction of new species

  • Biochemical parameters were nearer the normal levels in animals treated with this mushroom. These results suggest that administration of Agaricus silvaticus Schaeff ex

  • Active А2, А3, А4 group of extracts did not show any spot and picks by Thin layer chromatography (TLC) and HPLC, where there are no necessities to additional study or change of methodology; phytochemistry study was performed in A5 and A6 extracts separating them by column chromatography

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Summary

Introduction

Mushrooms are considered nutraceuticals or functional foods by many clinicians and researchers, a fact that has stimulated the search by Brazilian producers for more advanced production techniques along with introduction of new species. Agaricus silvaticus is able to reduce anemia and improve biochemical parameters in animals with cancer and has no adverse effects on the blood cells of healthy animals. Agaricus silvaticus treatment was able to reduce anemia in animals with cancer. These results suggest that administration of Agaricus silvaticus Schaeff ex.

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