Abstract
A 35-year-old black man complaining of chronic pain and redness of both lips presented, at oral examination, erosion and desquamation of lip vermilion and the commissures were fissured. From the clinical hypothesis of cheilitis glandularis, a biopsy of minor salivary gland was taken. The histologic examination revealed fragments of accessory salivary gland showing infiltration by mononuclear inflammatory cells at the connective tissue, and variable degrees of duct ectasia, resulting in chronic sialoadenitis. This finding confirmed the clinical diagnose and the patient started the treatment with intralesional steroid application with symptoms relief. Cheilitis glandularis is an uncommon chronic inflammatory disease of the lip minor salivary glands, especially in both lips, and presents a non-specific and challenging treatment. Cheilitis glandularis is not a life-threatening condition, but may affect the quality of life of the affected patients due to constant lip desquamation that can be symptomatic and can affect social interaction.
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