Charged ultrafiltration membrane for permeation of proteins

Abstract

AbstractPolyacrylonitrile‐g‐poly(N,N‐dimethylaminoethyl methacrylate) was synthesized photochemically and quaternized. The positively charged membranes made from the quaternized graftcopolymer showed high ultrafiltration rate for water by adding poly(vinyl alcohol) to casting solution and washing it out after the casting. In buffered saline solution, the permeability of the membranes was very small at pH below isoelectric point of albumin but increased markedly at higher pH. On the other hand, the permeability for γ‐globulin was very small and did not show any pH dependence.