Charge Transfer in DNA

Abstract

Foreword. Preface. List of Contributors. 1 Principles and Mechanisms of Photoinduced Charge Injection, Transport, and Trapping in DNA (Hans-Achim Wagenknecht). 1.1 Introduction. 1.2 Synthetic DNA-Donor-Acceptor Systems. 1.3 Photoinduced Oxidative Hole Transfer vs. Reductive Electron Transfer in DNA. 1.4 Hole Transfer and Hole Hopping in DNA. 1.5 Reductive Electron Transfer in DNA. 1.6 Conclusions. 2 Sequence-dependent DNA Dynamics: The Regulator of DNA-mediated Charge Transport (Melanie A. O'Neill and Jacqueline K. Barton). 2.1 Introduction. 2.2 Experimental Approaches to Studies of DNA-mediated Charge Transport Over Varied Energetic and Time Regimes. 2.3 Understanding the Fundamental Parameters Governing DNA-mediated Charge Transport. 2.4 A Mechanistic Model for DNA-mediated Charge Transport: Beyond Superexchange and Incoherent Hopping. 2.5 DNA-mediated Charge Transport in Biology. 2.6 Conclusions and Outlook. 3 Excess Electron Transfer in DNA Probed with Flavin- and Thymine Dimer-modified Oligonucleotides (Thomas Carell and Martin von Meltzer). 3.1 Introduction. 3.2 Excess Electron Transfer-driven DNA Repair by DNA Photolyases. 3.3 Excess Electron Transfer in DNA. 3.4 The Catalytic Electron? Or, Can One Electron Repair More Than One Dimer Lesion? 3.5 Future Directions. 4 Dynamics of Photoinitiated Hole and Electron Injection in Duplex DNA (Frederick D. Lewis and Michael R. Wasielewski). 4.1 Introduction. 4.2 DNA Hairpin Synthesis, Structure, and Energetics. 4.3 Hole Injection. 4.4 Hole Transport. 4.5 Electron Injection. 5 Spectroscopic Investigation of Oxidative Hole Transfer via Adenine Hopping in DNA (Kiyohiko Kawai and Tetsuro Majima). 5.1 Introduction. 5.2 Kinetics of Hole Transfer in DNA by Adenine Hopping. 5.3 Long-lived, Charge-separated State in DNA by Adenine Hopping. 5.4 Effect of Hole Transfer on Photosensitized DNA Damage. 5.5 Conclusions. 6 Chemical Probing of Reductive Electron Transfer in DNA (Steven E. Rokita and Takeo Ito). 6.1 Introduction. 6.2 A Reaction-based Method to Characterize Excess Electron Transfer. 6.3 Structural Dependence of BrU Reduction in DNA by Excess Electron Transfer. 6.4 General Conclusions and Future Prospects. 7 Chemical Approach to Modulating Hole Transport Through DNA (Chikara Dohno and Isao Saito). 7.1 Introduction. 7.2 Hole-injection Systems. 7.3 Modulation of Hole Transport Efficiency. 7.4 Modulation of Hole Trapping. 7.5 Conclusions. 8 Spectroscopic Investigation of Charge Transfer in DNA (Vladimir Shafirovich and Nicholas E. Geacintov). 8.1 Introduction. 8.2 Two-photon Ionization of 2-Aminopurine in DNA. 8.3 Oxidation of Guanine Residues by 2-Aminopurine Radicals in DNA. 8.4 End Products of Guanine Oxidation. 8.5 Concluding Remarks. 9 Electron Transfer and Structural Dynamics in DNA (Hans-Achim Wagenknecht and Torsten Fiebig). 9.1 Introduction. 9.2 Pyrene-modified Nucleosides as Model Systems for Electron Transfer in DNA. 9.3 Pyrene as an Electron Injector and a Probe for Base Dynamics in DNA. 9.4 Reductive Electron Transfer in Phenothiazine-modified DNA. 9.5 Structural Flexibility and Base Dynamics in Py dU-Modified DNA. 9.5.2 Spectral Properties, Dynamics, and Structural Information. 9.6 Ethidium as an Artificial Base and Charge Donor in DNA. 9.7 Conclusions and Outlook. Subject Index.