Abstract
Diabetes is the most common endocrine disorder of carbohydrate metabolism. If left untreated, or improperly treated for many years, diabetes leads to multiple organ complications. One of the serious consequences of the disease is damage to the peripheral and autonomic nerves known as diabetic neuropathy. The most advanced form of neuropathy, leading to damage to the structures of the forefoot, midfoot and hindfoot, is the so called Charcot foot, or neuropathic osteoarthropathy. Irreversible damage to the structures of the foot affects between 0,1% and 7.5% of patients with diabetes.
 The optimal care for that form of foot damage is still a subject to debate. Available methods of caring for Charcot foot include invasive orthopedic treatment and conservative treatment. The use of negative pressure woudn therapy may be an effective, as well as transitional, way of managing Charcot foot.
Highlights
D IABETES mellitus is the most common endocrine disorder
Impaired metabolism of carbohydrates leads to numerous organ complications
Peripheral neuropathy relates to 29% of patients with diabetes mellitus.[7]
Summary
D IABETES mellitus is the most common endocrine disorder. Impaired metabolism of carbohydrates leads to numerous organ complications. In 2011 there were 285 million patients with diagnosed diabetes. 2.5% will develop one of the most dangerous complications of diabetic foot, which is the Charcot arthropathy.[1]. Complicated form of diabetes is the most common cause of neuropathic arthropathy in developed countries. Charcot arthropathy is often diagnosed during the inactive, chronic stage when inflammatory symptoms are not present. In this phase, bones, joints and ligamentous apparatus of the foot are being continuously damaged. Eichenholtz described in his monograph cases of various osteoarticular lesions on the basis of 68 available radiograms, and introduced the term "Charcot joint".6 (Tab. I)
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