Characterizing the early and late asthmatic responses in the allergen inhalation challenge

Abstract

Allergen inhalation challenges (AICs) are widely used in research to assess airway responses to allergen exposure and predict the therapeutic effectiveness of various medications.1 The characteristics of early asthmatic response (EAR) and late asthmatic response (LAR) are often described in general terms.2-4 Original research findings focus on mean data. We are not aware of any data objectively documenting the responses of individual participants, and it is important to acknowledge that mean data do not accurately reflect the range of individual responses and the relevant safety implications of performing AICs.