Abstract

The proper packaging of DNA in sperm is absolutely necessary for human reproduction. Sperm nuclear DNA is tightly condensed, ensuring that the sperm is hydrodynamic and compact. This process is achieved using the sperm nuclear protein protamine, which directly or indirectly replaces the histones in somatic progenitor cells during spermiogenesis. Malfunctions of the histone replacement process are a known cause of male infertility. Our goal is twofold. We will examine partial histone wrapping states, which may play a key role in the histone replacement pathway.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.