Characterization, Properties and Antimicrobial Activity of Radiation Induced Phosphorus-Containing PVA Hydrogels

Abstract

Function modification of polyvinyl alcohol (PVA) having phosphorus-containing heterocyclic compounds is believed to have thermal and biological applications in the area of polymers. The synthesis of phosphorus-containing PVA (P-PVA) was performed using γ-radiation. The chemical structure of the composite polymer is confirmed by spectroscopic techniques of FT-IR, 1H, 13C, and 31P-NMR. Photosensitive properties of polymers were investigated by ultraviolet spectroscopy. Thermal studies are assigned using the Differential Scanning Calorimeter (DSC) and thermogravimetric analysis (TGA). Data display that P-PVA has more thermal stability than PVA. The surface morphology of the prepared hydrogels was performed using scanning electron microscopy (SEM). Quantitative elemental analysis of the P-PVA hydrogel was done through energy-dispersive X-ray spectroscopy (EDX). Antimicrobial activity of the prepared hydrogels using different fungi such as Aspergillus fumigatus, Geotrichum candidum, Candida albicans, and Syncephal-astrum racemosum, in addition to bacteria such as Staphylococcus aureus, Bacillis subtilis (as gram-positive bacteria), Pseudomonas aeruginosa, and Escherichia coli (as gram-negative bacteria), was studied. The phosphorus-contained PVA hydrogels were found to have antimicrobial activity against various fungi and bacteria compared to pure PVA hydrogels.