Abstract
In the present work melt-derived route was employed to fabricate new compositions of bioactive glasses (BG) from SiO2-CaO-Na2O-P2O5 system. Thermal analyses indicated all compositions can be melted at lower temperature than 1400°C. X-ray fluorescence (XRF) revealed that the amount of SiO2 and Na2O detected within the fabricated glass was significantly different compared to the initial weight measured during glass compositions preparation. X-ray diffraction (XRD) confirmed the amorphous glass structure for all glass compositions. Formation of silica network is established with the existence of functional group Si-O-Si (tetrahedral), confirmed with Fourier transform infrared spectroscope (FTIR) analyses. The bioactivity of all BG is evaluated by incubating the BGs in Hank's Balanced Salt Solution (HBSS) for 1h, 24h, 7 and 30days. The finding showed that all glass compositions remained in amorphous structure even after 30days of immersion with weak characteristic of carbonate group (C-O) and P-O band detected in FTIR analysis on carbonated hydroxyapatite (CHA) formation.
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