Abstract
The oryx bacilli are Mycobacterium tuberculosis complex organisms for which phylogenetic position and host range are unsettled. We characterized 22 isolates by molecular methods and propose elevation to subspecies status as M. orygis. M. orygis is a causative agent of tuberculosis in animals and humans from Africa and South Asia.
Highlights
The oryx bacilli are Mycobacterium tuberculosis complex organisms for which phylogenetic position and host range are unsettled
The Study We selected 22 isolates on the basis of >90% similarity of the IS6110 restriction fragment-length polymorphism (RFLP) pattern to that of established and previously published oryx bacillus strains; 11 isolates originated from animals, and 11 originated from 10 human patients (Figure 1) [1,2,3]
The oryx bacillus is a phylogenetically distinct lineage of the clonal M. tuberculosis complex and deserves a separate subspecies status; we propose the name M. orygis (Latin: oryx, genitive: orygis, of the oryx) to convey that this subspecies was first characterized after its isolation from an oryx (Figure 2)
Summary
The oryx bacilli are Mycobacterium tuberculosis complex organisms for which phylogenetic position and host range are unsettled. No human disease caused by the oryx bacilli has been reported. The Study We selected 22 isolates on the basis of >90% similarity of the IS6110 restriction fragment-length polymorphism (RFLP) pattern to that of established and previously published oryx bacillus strains; 11 isolates originated from animals, and 11 originated from 10 human patients (Figure 1) [1,2,3].
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