Abstract
Fused silica capillaries with an i.d. of 50 and 75 μm are chemically modified by the silanization/hydrosilation method to attach organic moieties for use in electrokinetic chromatography. An etching process was utilized to increase the surface area of the capillary inner wall. A comparison of Si-C bonded capillary columns to those obtained by conventional organosilanization (Si-O-Si-C) bond was performed. The etched capillaries after chemical modification are shown to have an anodic electroosmotic flow (EOF) below pH 4.5 while the bare modified capillaries show a cathodic EOF at all pH's studied. The use of these etched chemically modified capillaries eliminates the need for frits and the difficulties associated with packed capillaries such as bubble formation. This open tubular approach to CEC is also suitable for an analysis of a number of different types of basic compounds.
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