Abstract
To analyze the profile of airway Upper Respiratory Tract isolates from children with recurrent tonsillitis. Samples were taken using nasal cavity, oropharynx and nasopharynx swabs from30 children called the test group before tonsillectomy. Counting, isolation, identification and sequencing of the 16S rRNA, biofilm production and antimicrobial sensitivity investigation were performed. Staphylococcus aureus (S. aureus) was the only microorganism recovered in 36.6% of patients, being more present in the oropharynx and with greater resistance to erythromycin 95%, penicillin 85% and cefoxitin 85%. All isolates were formed by biofilm, 20% formed by strongly adherent biofilm. S. aureus resistant and biofilm formed, were isolated in the three studied sites, suggesting that this species contributes to recurrent tonsillitis. Impact of the study: The ability of S. aureus to acquire resistance and its other associated factors such as biofilm formation, can make this microorganism recover more easily in the microbiota of patients, taking into account the other microorganisms present there after the use of antibacterial.
Highlights
The microbiota of a site is defined by the presence of microorganisms and their metabolites present in the different sites of the host (Thursby and Juge2017)
Published studies describe the prevalence of potentially pathogenic bacteria found in pediatric patients with recurrent tonsillitis, including Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Haemophilusinfluenzae and Moraxella catarrhalis (Kalaiarasi et al, 2018; Prates et al 2018)
We conclude that S. aureus can be isolated from any of the studied sites, suggesting that the three sites should be used for the collection of clinical specimens in case of investigation
Summary
The microbiota of a site is defined by the presence of microorganisms and their metabolites present in the different sites of the host (Thursby and Juge2017). Each site has its own microbiota, with specific species(Coyte et al, 2015). The airway Upper Respiratory Tract (URT) is divided into two parts, the upper and the lower and, each of these sites has a specific microbiota, the URT microbiota is distinct from each other and has patterns of colonization and succession. URT has been colonized by bacterial species of different genera, such as Streptococcus spp., Haemophilus spp., Coagulase negative Staphylococcus, Streptococcus viridans, Haemophilusinfluenzae, Streptococcus pneumoniae, Moraxella catarrhalis and Staphylococcus spp. Respiratory tract infections are described when they affect the respiratory tract, both upper and lower, in which there is obstruction of the air passage, both at the nasal and pulmonary levels (World Health Organization 2014) being a major concern worldwide, as they are responsible for high morbidity and mortality, especially in children and the elderly(de. Frequent, when infection occurs in URT, they usually do not cause death, but significantly interfere with the individual's quality of life, in addition to generating costs for the country's health
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