Abstract
Purpose: Calcifications in joint soft tissues, such as meniscus and articular cartilage, are closely associated with osteoarthritis (OA) progression and could act as a potential target for disease-modifying agents in OA therapy. Basic calcium phosphate (BCP) and calcium pyrophosphate dihydrate (CPPD) crystals are the two most common forms of calcium crystals found in these tissues. Moreover, within the CPPD crystals, two different polymorphs - monoclinic and triclinic - have been identified in arthritic patients.
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